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As ice crystals form, they can exert immense physical pressure on the peptide molecules, shearing and denaturing them

It serves as a diluent for medications that require reconstitution before injection, particularly those intended for one-time use

Some commenters recommended CMS collect MA negotiated data from hospital or payor websites via MRFs or gather it directly since CMS already contracts with MAO plans, rather than requiring hospitals to extract and re-report the same information on the cost report, to avoid unnecessary administrative burden